keyboard and mouse not working

I was playing today and was in town of act 3. I changed some skills around and went back to the black chamber and all of the sudden i couldn't move anymore. I was at the waypoint and it would let me go back to town, but when I'm in any other playable area i can't move. I changed it to the ASWD and i can move. That isn't what i want to do. Does anyone have any ideas on how to fix this? I don't know why the keyboard ad mouse work in town but not in game. Has this happened to anyone else? Thanks is advance for any help or ideas.